Protonix is an inhibitor of H+/K+ ATPase. It blocks the final stage of secretion of hydrochloric acid, reduces the level of basal and stimulated secretion of hydrochloric acid in the stomach. Protonix has an antimicrobial activity against Helicobacter pylori. Generic Protonix is made by the pharmaceutical company Wockhardt.
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- Product Description
- Side Effects
- Safety Information
Drug name: Protonix (Pantoprazole)
Therapeutic effects:
Protonix is a drug used to treat ulcers. Protonix (Pantoprazole) accumulates in the tubules of gastric parietal cells and transformes into an active form - cyclic sulfenamide which selectively interacts with H+/K+ ATPase. Pantoprazole inhibits H+/K+ ATPase of parietal cells, violates the transfer of hydrogen ions from the parietal cells into the lumen of the stomach and blocks the final stage of the hydrophilic secretion of hydrochloric acid. Suppresses basal and stimulated secretion of hydrochloric acid.
Protonix also has an antibacterial effect against Helicobacter pylori. Therapeutic effect after a single dose occurs quickly and persists for 24 hours.
Indications:
- Stomach ulcer and duodenal ulcer in acute phase
- Zollinger-Ellison syndrome
- Eradication of Helicobacter pylori (in combination with antibiotic therapy)
- Reflux esophagitis
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